About
Triglimisave 1mg is a triple-combination oral antidiabetic medication containing Glimepiride, Metformin, and Pioglitazone, formulated for effective glycemic management in adults with type 2 diabetes mellitus. Glimepiride, a sulfonylurea, stimulates the pancreas to release insulin. Metformin, a biguanide, works by decreasing glucose production in the liver and improving the body's response to insulin. Pioglitazone, a thiazolidinedione, enhances insulin sensitivity in peripheral tissues and the liver. This comprehensive approach targets multiple pathophysiological defects of type 2 diabetes, providing robust control over blood glucose levels. It is typically prescribed when diet, exercise, and dual therapy have not achieved adequate glycemic targets, offering a multi-pronged strategy for diabetes management.
Uses
- Treatment of type 2 diabetes mellitus.
- Improvement of glycemic control in adults.
- Used when diet, exercise, and dual therapy are insufficient.
- Reduction of fasting and post-prandial glucose levels.
Directions For Use
Take this medication orally, usually once daily with a meal, as directed by your healthcare provider.
Benefits
- Comprehensive blood sugar control.
- Targets multiple diabetes mechanisms.
- Significantly lowers HbA1c.
- Improves insulin sensitivity.
- Reduces hepatic glucose production.
- Convenient fixed-dose combination.
Side Effects
- Hypoglycemia (due to Glimepiride)
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Weight gain
- Peripheral edema
- Lactic acidosis (rare, with Metformin)
- Bone fractures (with Pioglitazone)
- Heart failure (rare, with Pioglitazone)
- Upper respiratory tract infection
Safety Measures
- Alcohol - Avoid excessive alcohol consumption due to increased risk of hypoglycemia (with Glimepiride) and lactic acidosis (with Metformin).
- Pregnancy - Contraindicated during pregnancy. May cause fetal harm. Insulin is generally preferred for glycemic control in pregnant women.
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk.
- Liver - Contraindicated in active liver disease or severe hepatic impairment due to increased risk of lactic acidosis and liver toxicity.
- Kidney - Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²). Dose adjustment required for moderate impairment.
- Lung - Use with extreme caution in patients with a history of heart failure or pulmonary edema, as Pioglitazone can exacerbate fluid retention.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |
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