About
TRIMEGAVOG 1mg contains voglibose, an alpha-glucosidase inhibitor used in the management of type 2 diabetes mellitus. Voglibose works by reversibly inhibiting alpha-glucosidase enzymes in the small intestine, which are responsible for breaking down complex carbohydrates into absorbable monosaccharides. By delaying the digestion and absorption of carbohydrates, voglibose helps to reduce the rise in blood glucose levels that occurs after meals (postprandial hyperglycemia).
This medication is typically prescribed as an adjunct to diet and exercise, either as monotherapy or in combination with other oral antidiabetic agents, when diet and exercise alone are insufficient to control postprandial blood glucose. Its primary action on carbohydrate digestion makes it particularly effective in managing post-meal glucose spikes, contributing to overall glycemic control in adults with type 2 diabetes.
Uses
- Management of type 2 diabetes mellitus.
- Reduction of postprandial hyperglycemia.
- Used as an adjunct to diet and exercise.
- As monotherapy or in combination therapy.
Directions For Use
Take this medication orally, usually with the first bite of each main meal, as directed by your physician.
Benefits
- Effectively reduces postprandial blood glucose.
- Low risk of hypoglycemia as monotherapy.
- Does not cause weight gain.
- Can be used in combination with other agents.
- Improves overall glycemic control.
- Acts locally in the gastrointestinal tract.
Side Effects
- Flatulence
- Abdominal distension
- Diarrhea
- Abdominal pain
- Nausea
- Vomiting
- Constipation
- Indigestion
- Hypoglycemia (when combined with sulfonylurea or insulin)
- Increased liver enzymes (rare)
- Skin rash (rare)
- Ileus (very rare)
Safety Measures
- Alcohol - No specific contraindication with alcohol, but excessive intake should be discussed with a doctor as it can affect blood sugar levels.
- Pregnancy - Generally not recommended during pregnancy due to insufficient data. Consult a doctor; insulin is often preferred for glycemic control in pregnant women with diabetes.
- Breastfeeding - It is unknown if voglibose is excreted in human milk. Use with caution and under medical supervision, weighing potential risks to the infant against maternal benefits.
- Liver - Use with caution in patients with severe hepatic impairment. Regular monitoring of liver function tests may be advised.
- Kidney - Use with caution in patients with severe renal impairment. Dose adjustment may be necessary.
- Lung - No specific contraindications related to lung conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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