VELASOF TABS 28's

About

VELASOF TABS contain a combination of direct-acting antiviral agents, sofosbuvir and velpatasvir, specifically designed for the treatment of chronic hepatitis C virus (HCV) infection. This medication works by targeting key viral proteins, NS5B polymerase and NS5A protein, which are essential for HCV replication. By inhibiting these proteins, VELASOF effectively stops the virus from multiplying and spreading within the body. It is a highly potent, pan-genotypic regimen, meaning it is effective across all major HCV genotypes (1-6), offering a simplified treatment approach for a broad range of patients. Its high sustained virologic response (SVR) rates make it a cornerstone in modern HCV therapy, often leading to a cure with a relatively short treatment duration.

The combination therapy is well-tolerated and represents a significant advancement over older, interferon-based treatments, which were associated with more severe side effects and lower efficacy. VELASOF is crucial for preventing the progression of HCV-related liver disease, including cirrhosis, liver failure, and hepatocellular carcinoma, thereby improving long-term patient outcomes and quality of life. It can be used in patients with or without compensated cirrhosis, and in combination with ribavirin for those with decompensated cirrhosis.

Uses

• Chronic Hepatitis C virus (HCV) infection (genotypes 1-6)
• HCV infection in patients with compensated cirrhosis
• HCV infection in patients with decompensated cirrhosis (with ribavirin)
• HCV/HIV co-infection

Directions For Use

Take one tablet orally once daily with or without food, as directed by your physician.

Benefits

• High sustained virologic response (SVR) rates
• Broad pan-genotypic coverage (genotypes 1-6)
• Short treatment duration, typically 12 weeks
• Good tolerability profile compared to older regimens
• Interferon-free and ribavirin-free for most patients
• Effective in difficult-to-treat populations

Side Effects

• Headache
• Fatigue
• Nausea
• Diarrhea
• Insomnia
• Asthenia
• Rash
• Pruritus
• Anemia
• Irritability
• Muscle pain
• Dizziness

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can worsen liver disease and potentially interact with the medication.
• Pregnancy - Use only if the potential benefit justifies the potential risk to the fetus; consult your physician before use.
• Breastfeeding - Not recommended as it is unknown if the components are excreted in human milk. Consult your doctor.
• Liver - Generally safe and effective for liver conditions, including cirrhosis; no dose adjustment is typically needed.
• Kidney - No dose adjustment is needed for mild to moderate renal impairment; caution is advised in severe renal impairment.
• Lung - No specific lung-related precautions; generally safe for patients with lung conditions.

Disclaimer

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