ZETRI 1GM VIAL

About

ZETRI 1GM VIAL is a broad-spectrum antibiotic, likely a third-generation cephalosporin, designed for intravenous or intramuscular administration. It works by inhibiting bacterial cell wall synthesis, leading to the disruption of the bacterial cell structure and ultimately bacterial death. This mechanism of action makes it effective against a wide range of Gram-positive and Gram-negative bacteria, including many resistant strains.

Due to its potent bactericidal activity and favorable pharmacokinetic profile, ZETRI is commonly used to treat serious bacterial infections in various body systems. Its long half-life often allows for once-daily dosing, which can improve patient compliance and convenience. It is particularly valuable in hospital settings for empirical therapy of severe infections before specific pathogen identification, as well as for targeted treatment once susceptibility is confirmed.

Uses

• Treatment of severe respiratory tract infections.
• Management of complicated urinary tract infections.
• Therapy for skin and soft tissue infections.
• Treatment of bacterial meningitis and sepsis.

Directions For Use

Administer intravenously or intramuscularly as directed by a healthcare professional. Dosage and duration depend on the infection type, severity, and patient factors.

Benefits

• Broad-spectrum antibacterial activity.
• Effective against many resistant bacteria.
• Convenient once-daily dosing for some indications.
• Penetrates well into various body tissues.
• Suitable for severe and complicated infections.
• Can be used for empirical therapy.

Side Effects

• Diarrhea
• Nausea
• Vomiting
• Abdominal pain
• Injection site pain or tenderness
• Rash
• Allergic reactions (hives, itching)
• Eosinophilia
• Thrombocytosis
• Leukopenia
• Elevated liver enzymes
• Pseudomembranous colitis (rare)

Safety Measures

• Alcohol - Avoid alcohol consumption during treatment and for several days after, as some cephalosporins can cause a disulfiram-like reaction (nausea, vomiting, flushing, headache).
• Pregnancy - Generally considered safe for use during pregnancy, especially when clearly indicated, but should be used with caution and under medical supervision.
• Breastfeeding - Passes into breast milk in small amounts; generally considered compatible with breastfeeding, but monitor infant for potential side effects like diarrhea or rash.
• Liver - Use with caution in patients with severe liver impairment; dose adjustments may be necessary, and liver function should be monitored.
• Kidney - Dose adjustments are typically required in patients with significant renal impairment to prevent accumulation and toxicity.
• Lung - No specific contraindication related to lung conditions, but monitor for allergic reactions that may manifest as respiratory distress.

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