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Toritz 500mg Injection

Salt Composition: Rituximab  
Manufacturer: TORRENT PHARMACEUTICALS LTD  
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About

Toritz 500mg Injection contains the active ingredient rituximab and is used to treat various conditions in adults. It may be administered alone or with other medications to manage non-Hodgkin’s lymphoma (a cancer affecting B-lymphocytes) and chronic lymphocytic leukemia (a common B-cell cancer). It is also prescribed in combination with methotrexate for moderate-to-severe rheumatoid arthritis, an autoimmune disorder where the immune system attacks the joints. Additional approved uses include granulomatosis with polyangiitis and microscopic polyangiitis—both inflammatory diseases affecting blood vessels, mainly in the lungs and kidneys—in adults and children aged 2 years and older. Toritz is also used for moderate to severe pemphigus vulgaris, an autoimmune condition that causes painful blisters on the skin and mucous membranes of the mouth, throat, nose, and genitals.

Toritz 500mg Injection belongs to the class of anti-CD20 monoclonal antibodies. Do not use this injection if you are allergic to rituximab or any of its ingredients, have a weakened immune system, or have a severe active infection. Before starting treatment, inform your doctor if you have heart disease, heart failure, or breathing difficulties. Also, inform your doctor if you have ever had hepatitis B, as the infection may reactivate in some cases and can be serious. Pregnancy and breastfeeding are not recommended during treatment with this medication.

Common side effects of Toritz 500mg Injection include blood infections, low red blood cell counts, dizziness, swelling of the face and body, itching, diarrhea, excessive sweating, and changes in blood pressure (either high or low). Women who can become pregnant should use effective contraception during treatment and for 12 months after the final dose. This medication may cause severe infusion reactions during or within 24 hours after administration. Contact your doctor or healthcare professional immediately if you experience symptoms such as high blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rash, or throat swelling.

 Uses 

  • Rheumatoid Arthritis
  • Chronic lymphocytic leukemia (CLL)
  • Non-hodgkin’s lymphoma (NHL)
  • Pemphigus vulgaris
  • Granulomatosis with polyangiitis or microscopic polyangiitis

Directions for use

This medicine should be administered by a doctor or nurse. Please do not attempt to self-administer it.


Side effects 
    

  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Increased or decreased blood pressure
  • Chest pain
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin

    
Safety Measures

Alcohol - Drinking alcohol may reduce the effectiveness of Toritz 500mg Injection. It is advisable to avoid alcohol while undergoing treatment with this medication.
Pregnancy - Toritz 500mg Injection is not safe for use during pregnancy, as it may harm the developing fetus. Inform your doctor if you are pregnant, think you might be, or are planning to become pregnant. It is essential to use effective contraception during treatment and for 12 months after the final dose.
Breastfeeding - Breastfeeding is not recommended while taking Toritz 500mg Injection, as small amounts of the medicine can pass into breast milk and may potentially harm your baby.
Liver -The safety of Toritz 500mg Injection in patients with liver impairment is not well established. Consult your doctor if you have a history of liver disease or hepatitis B infection before beginning treatment, as reactivation of the hepatitis virus can lead to serious liver complications.
Kidney -The effects of Toritz 500mg Injection on the kidneys are not well known. Consult your doctor if you have any kidney-related conditions before starting treatment.

  Disclaimer

Med E Hub is committed to delivering reliable, expert-reviewed information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient reilationshp.

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