ZITEN 20 TAB 10.S

About

ZITEN 20 TAB contains Teneligliptin 20mg, an oral antidiabetic medication belonging to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It is used for the management of Type 2 Diabetes Mellitus. Teneligliptin works by selectively inhibiting the DPP-4 enzyme, which is responsible for the degradation of incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By preserving these incretins, Teneligliptin enhances glucose-dependent insulin secretion from pancreatic beta cells and suppresses glucagon secretion from alpha cells, particularly after meals.

This mechanism of action leads to improved control of both fasting and post-meal blood glucose levels without significantly increasing the risk of hypoglycemia, as its effects are glucose-dependent. ZITEN 20 TAB is often prescribed when diet and exercise alone are insufficient, or as an add-on therapy to other antidiabetic agents like Metformin. Its ability to improve beta-cell function and reduce HbA1c makes it a valuable option in preventing the long-term complications associated with uncontrolled Type 2 diabetes, such as cardiovascular disease, kidney damage, and nerve problems.

Uses

• Management of Type 2 Diabetes Mellitus.
• As monotherapy when diet and exercise are insufficient.
• As an add-on therapy to other antidiabetic agents.
• To improve glycemic control and reduce HbA1c.

Directions For Use

Take orally, usually once daily, with or without food, as directed by your physician. Swallow the tablet whole.

Benefits

• Effectively lowers both fasting and post-meal blood glucose.
• Significantly reduces HbA1c levels.
• Low risk of hypoglycemia due to glucose-dependent action.
• Weight neutral, does not cause weight gain.
• Convenient once-daily dosing.
• Improves pancreatic beta-cell function.

Side Effects

• Nasopharyngitis (common cold symptoms)
• Headache
• Dizziness
• Constipation
• Diarrhea
• Abdominal discomfort
• Pancreatitis (rare, serious)
• Skin rash
• Urticaria (hives)
• Angioedema (swelling under the skin)
• Joint pain
• Muscle pain
• Fatigue

Safety Measures

• Alcohol - Generally safe, but excessive alcohol consumption can affect blood glucose levels. Monitor closely.
• Pregnancy - Not recommended during pregnancy due to insufficient data. Consult your doctor immediately if pregnant or planning pregnancy.
• Breastfeeding - Not recommended during breastfeeding as it is unknown if Teneligliptin is excreted in breast milk. Consult your doctor.
• Liver - Use with caution in patients with moderate to severe hepatic impairment. Dose adjustment may be considered.
• Kidney - No dose adjustment typically required for mild to moderate renal impairment; use with caution in severe impairment.
• Lung - No specific contraindications or precautions related to lung conditions.

Disclaimer

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