Celonib 100mg Tablet

About

Celonib 100mg Tablet is a targeted therapy belonging to the class of tyrosine kinase inhibitors (TKIs). It functions by selectively blocking specific enzymes, known as tyrosine kinases, which are crucial for cell growth and proliferation in certain types of cancer. By inhibiting these aberrant signaling pathways, Celonib helps to slow down or stop the growth of cancer cells, leading to disease control and potential tumor regression. This targeted approach often allows for a more precise intervention compared to traditional chemotherapy, aiming to minimize damage to healthy cells while effectively combating malignant ones. It is typically used in the management of various solid tumors and hematological malignancies where these specific pathways are overactive.

The drug's mechanism involves interfering with the signals that tell cancer cells to grow and divide, thereby inducing apoptosis (programmed cell death) or arresting the cell cycle. Its efficacy is often dependent on the presence of specific genetic mutations or biomarkers in the tumor, which guide its clinical application. Regular monitoring of patient response and potential side effects is essential throughout the treatment course to ensure optimal outcomes and patient safety.

Uses

• Treatment of certain solid tumors
• Management of specific hematological malignancies
• Inhibition of abnormal cell growth pathways
• Targeted therapy for advanced cancers

Directions For Use

Take this medicine orally as directed by your physician, usually once daily. It can be taken with or without food.

Benefits

• Targets specific cancer-driving pathways
• May offer improved progression-free survival
• Potentially better tolerability than conventional chemotherapy
• Oral administration for convenience
• Helps to control tumor growth and spread
• Effective in biomarker-selected patient populations

Side Effects

• Fatigue
• Nausea
• Diarrhea
• Skin rash
• Peripheral edema
• Hypertension
• Myelosuppression (low blood counts)
• Headache
• Abdominal pain
• Elevated liver enzymes
• Proteinuria
• Hand-foot syndrome

Safety Measures

• Alcohol - Limit or avoid alcohol consumption as it may exacerbate liver strain and other side effects.
• Pregnancy - Celonib is contraindicated during pregnancy due to potential fetal harm. Effective contraception is required.
• Breastfeeding - Not recommended during breastfeeding as the drug may pass into breast milk and harm the infant.
• Liver - Use with caution in patients with liver impairment; dose adjustments may be necessary. Monitor liver function regularly.
• Kidney - Use with caution in patients with kidney impairment; dose adjustments may be necessary. Monitor renal function regularly.
• Lung - Monitor for signs of interstitial lung disease or pneumonitis, such as new or worsening cough and shortness of breath.

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