Cilacar 10mg Tablet

About

Cilacar 10mg Tablet contains Cilnidipine, a dihydropyridine calcium channel blocker used to treat essential hypertension. It works by inhibiting the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and a reduction in peripheral vascular resistance. A distinctive feature of Cilnidipine is its dual blockade of both L-type and N-type calcium channels. The L-type channel blockade primarily relaxes arterial smooth muscles, contributing to its antihypertensive effect. The N-type channel blockade helps to suppress sympathetic overactivity, which can mitigate reflex tachycardia often associated with other calcium channel blockers. This unique mechanism provides effective and sustained blood pressure control, reducing the risk of cardiovascular events like strokes, heart attacks, and kidney damage. Its sustained action allows for once-daily dosing, providing consistent blood pressure management. Cilnidipine is well-absorbed orally and metabolized in the liver, with excretion primarily through the kidneys and feces, making it suitable for various patient populations, including those with mild to moderate renal impairment under medical supervision.

Uses

• Treatment of essential hypertension
• Management of high blood pressure
• Prevention of cardiovascular complications
• Adjunctive therapy in certain hypertensive conditions

Directions For Use

Take this medicine as prescribed by your doctor, usually once daily. It can be taken with or without food.

Benefits

• Effectively lowers high blood pressure
• Reduces risk of heart attack and stroke
• Provides sustained blood pressure control
• May offer renoprotective effects
• Less likely to cause ankle edema compared to other CCBs
• Helps manage sympathetic overactivity

Side Effects

• Headache
• Dizziness
• Flushing
• Palpitations
• Ankle swelling (edema)
• Fatigue
• Nausea
• Abdominal discomfort
• Gingival hyperplasia
• Rash
• Hypotension
• Increased urination

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may increase the blood pressure-lowering effect and enhance side effects like dizziness.
• Pregnancy - Generally not recommended during pregnancy unless clearly necessary, as safety data are limited. Consult your doctor.
• Breastfeeding - Use with caution during breastfeeding. It is unknown if Cilnidipine passes into breast milk. Seek medical advice.
• Liver - Use with caution in patients with liver impairment. Dosage adjustment may be necessary.
• Kidney - Generally safe for use in patients with mild to moderate kidney conditions, but severe impairment requires careful monitoring.
• Lung - No specific contraindications for lung conditions, but always inform your doctor about pre-existing respiratory issues.

Disclaimer

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