AboutCilacar 20mg Tablet contains Cilnidipine, a dihydropyridine calcium channel blocker used to treat essential hypertension. It works by inhibiting the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and a reduction in peripheral vascular resistance. A distinctive feature of Cilnidipine is its dual blockade of both L-type and N-type calcium channels. The L-type channel blockade primarily relaxes arterial smooth muscles, contributing to its antihypertensive effect. The N-type channel blockade helps to suppress sympathetic overactivity, which can mitigate reflex tachycardia often associated with other calcium channel blockers. This unique mechanism provides effective and sustained blood pressure control, reducing the risk of cardiovascular events like strokes, heart attacks, and kidney damage. Its sustained action allows for once-daily dosing, providing consistent blood pressure management. Cilnidipine is well-absorbed orally and metabolized in the liver, with excretion primarily through the kidneys and feces, making it suitable for various patient populations, including those with mild to moderate renal impairment under medical supervision.UsesTreatment of essential hypertensionManagement of high blood pressurePrevention of cardiovascular complicationsAdjunctive therapy in certain hypertensive conditionsDirections For UseTake this medicine as prescribed by your doctor, usually once daily. It can be taken with or without food.BenefitsEffectively lowers high blood pressureReduces risk of heart attack and strokeProvides sustained blood pressure controlMay offer renoprotective effectsLess likely to cause ankle edema compared to other CCBsHelps manage sympathetic overactivitySide EffectsHeadacheDizzinessFlushingPalpitationsAnkle swelling (edema)FatigueNauseaAbdominal discomfortGingival hyperplasiaRashHypotensionIncreased urinationSafety MeasuresAlcohol - Avoid or limit alcohol consumption as it may increase the blood pressure-lowering effect and enhance side effects like dizziness.Pregnancy - Generally not recommended during pregnancy unless clearly necessary, as safety data are limited. Consult your doctor.Breastfeeding - Use with caution during breastfeeding. It is unknown if Cilnidipine passes into breast milk. Seek medical advice.Liver - Use with caution in patients with liver impairment. Dosage adjustment may be necessary.Kidney - Generally safe for use in patients with mild to moderate kidney conditions, but severe impairment requires careful monitoring.Lung - No specific contraindications for lung conditions, but always inform your doctor about pre-existing respiratory issues.DisclaimerMedEHub is committed to delivering reliable, expert-reviewd information to help consumers make
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