ESLO AT

About

ESLO AT is a fixed-dose combination medication used for the effective management of hypertension (high blood pressure) and angina pectoris. It comprises Amlodipine, a dihydropyridine calcium channel blocker, and Atenolol, a beta-1 selective adrenergic receptor blocker. Amlodipine primarily acts by relaxing the smooth muscles in the walls of blood vessels, leading to vasodilation and a reduction in peripheral vascular resistance, thereby lowering blood pressure. It also improves blood flow to the heart, which helps in relieving angina. Atenolol works by selectively blocking beta-1 receptors in the heart, which reduces heart rate, myocardial contractility, and cardiac output, further contributing to blood pressure reduction and decreasing the heart's oxygen demand, thus preventing angina attacks. This synergistic action provides comprehensive control over blood pressure and angina symptoms, making it a valuable option for patients requiring dual therapy.

Uses

• Treatment of essential hypertension (high blood pressure).
• Management of chronic stable angina pectoris.
• Prevention of angina attacks.
• Improvement of cardiovascular outcomes in hypertensive patients.

Directions For Use

Take once daily, preferably at the same time each day, with or without food, as prescribed by your doctor.

Benefits

• Effective blood pressure reduction.
• Dual mechanism for comprehensive control.
• Reduces frequency and severity of angina.
• Convenient once-daily dosing.
• Improved cardiac workload.
• Reduced risk of cardiovascular events.

Side Effects

• Bradycardia (slow heart rate)
• Dizziness
• Fatigue
• Headache
• Edema (swelling, especially ankles)
• Nausea
• Cold extremities
• Shortness of breath
• Insomnia
• Muscle cramps
• Depression
• Gastrointestinal disturbances

Safety Measures

• Alcohol - Avoid or limit alcohol as it can further lower blood pressure and increase dizziness.
• Pregnancy - Not recommended, especially in the second and third trimesters, due to potential fetal harm; consult a doctor.
• Breastfeeding - Not recommended; components may pass into breast milk and affect the infant.
• Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary.
• Kidney - Use with caution in patients with kidney impairment; dose adjustment may be necessary.
• Lung - Contraindicated in severe obstructive airway diseases (e.g., severe asthma, COPD) due to the beta-blocker component.

Disclaimer

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