LISPA SR CAP 10S

About

Lispa SR Cap likely contains Metformin, a widely used oral biguanide medication for the management of type 2 diabetes mellitus. As a sustained-release formulation, it is designed to release the active ingredient slowly over time, which can improve gastrointestinal tolerability and allow for once-daily dosing. Metformin primarily works by decreasing glucose production in the liver, reducing glucose absorption from the intestines, and improving the body's sensitivity to insulin.

This medication helps to lower elevated blood glucose levels and improve glycemic control in adults with type 2 diabetes, typically used as an adjunct to diet and exercise. It does not usually cause hypoglycemia when used alone. Metformin has also been associated with modest weight loss and may offer cardiovascular benefits. Regular monitoring of kidney function and vitamin B12 levels is important during long-term treatment.

Uses

• To improve glycemic control in adults with type 2 diabetes mellitus.
• As an adjunct to diet and exercise.
• To reduce the risk of diabetes-related complications.
• In patients who cannot tolerate immediate-release metformin due to GI side effects.

Directions For Use

Take orally once daily with the evening meal, or as directed by your physician. Swallow the capsule whole; do not crush or chew.

Benefits

• Effectively lowers blood glucose levels.
• Reduced gastrointestinal side effects compared to immediate-release.
• Convenient once-daily dosing.
• Does not typically cause weight gain.
• May reduce cardiovascular risk.
• Improves insulin sensitivity.

Side Effects

• Diarrhea
• Nausea
• Vomiting
• Abdominal discomfort
• Flatulence
• Metallic taste in mouth
• Headache
• Dizziness
• Hypoglycemia (rare, when used alone)
• Lactic acidosis (rare, but serious)
• Vitamin B12 deficiency
• Weakness

Safety Measures

• Alcohol - Avoid excessive alcohol intake as it significantly increases the risk of lactic acidosis and can cause hypoglycemia.
• Pregnancy - Metformin use during pregnancy should be discussed with a doctor; insulin is often preferred.
• Breastfeeding - Metformin passes into breast milk; generally considered compatible, but consult your doctor.
• Liver - Contraindicated in severe liver impairment due to increased risk of lactic acidosis.
• Kidney - Contraindicated in severe kidney impairment (eGFR <30 mL/min/1.73 m²); dose adjustments for moderate impairment.
• Lung - Generally safe, but acute/chronic lung disease with hypoxia can increase lactic acidosis risk.

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