Lupinib 400mg Tablet

About

Lupinib 400mg Tablet is a potent and selective tyrosine kinase inhibitor (TKI) primarily used in the treatment of certain advanced cancers. It works by targeting and inhibiting specific protein kinases, such as BCR-ABL, which are crucial for the growth, survival, and proliferation of cancer cells. By blocking these aberrant signaling pathways, Lupinib effectively helps to halt the progression of the disease, reduce tumor burden, and induce apoptosis in malignant cells. This targeted therapeutic approach offers a significant advantage by minimizing damage to healthy cells compared to conventional chemotherapy, making it a cornerstone in the management of specific hematological and solid tumors. Its efficacy has been well-demonstrated in patients with particular genetic mutations, leading to improved clinical outcomes and prolonged survival.

Uses

• Treatment of chronic myeloid leukemia (CML).
• Management of gastrointestinal stromal tumors (GIST).
• Therapy for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL).
• Treatment of myelodysplastic/myeloproliferative diseases.

Directions For Use

Take orally once daily with a meal and a large glass of water, as directed by your oncologist.

Benefits

• Targeted therapy for specific cancers.
• Improves progression-free survival.
• Oral administration for convenience.
• Effective in specific genetically defined tumors.
• May offer a better quality of life than conventional chemotherapy.
• Reduces tumor burden and disease progression.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Muscle cramps
• Fluid retention (edema)
• Rash
• Fatigue
• Headache
• Abdominal pain
• Myelosuppression (low blood counts)
• Elevated liver enzymes
• Periorbital edema

Safety Measures

• Alcohol - Avoid alcohol as it may exacerbate liver toxicity and other side effects.
• Pregnancy - Contraindicated; can cause fetal harm. Effective contraception is required.
• Breastfeeding - Contraindicated; the drug may be excreted in breast milk and harm the infant.
• Liver - Use with caution; dose adjustment may be necessary in patients with hepatic impairment.
• Kidney - Use with caution; dose adjustment may be necessary in patients with renal impairment.
• Lung - Monitor for signs of pulmonary toxicity, including interstitial lung disease or pneumonitis.

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