About
Metstop AM 50/5 combines two potent cardiovascular medications: metoprolol, a beta-blocker, and amlodipine, a dihydropyridine calcium channel blocker. Metoprolol works by selectively blocking beta-1 adrenergic receptors, reducing heart rate, myocardial contractility, and blood pressure. Amlodipine, on the other hand, relaxes vascular smooth muscle, leading to vasodilation and a decrease in peripheral vascular resistance, which also lowers blood pressure. This synergistic combination provides comprehensive control over hypertension and angina by addressing different physiological pathways. It is particularly useful for patients who require more aggressive blood pressure management or those who experience angina pectoris, offering improved efficacy compared to monotherapy. The dual mechanism helps to achieve target blood pressure more effectively while potentially minimizing the dose-dependent side effects of each component when used alone, thereby enhancing patient adherence and overall cardiovascular outcomes.
Uses
- Treatment of essential hypertension.
- Management of chronic stable angina pectoris.
- Reduction of cardiovascular risk in hypertensive patients.
- Improvement of symptoms in patients with coronary artery disease.
Directions For Use
Take one tablet orally once daily, preferably at the same time each day, with or without food, as prescribed by your doctor.
Benefits
- Provides effective blood pressure control.
- Reduces the frequency and severity of angina attacks.
- Offers dual-action mechanism for comprehensive treatment.
- May reduce the risk of cardiovascular events.
- Improves patient compliance with a single pill.
- Helps protect the heart from excessive strain.
Side Effects
- Dizziness
- Headache
- Fatigue
- Bradycardia (slow heart rate)
- Edema (swelling, especially ankles)
- Nausea
- Abdominal pain
- Flushing
- Palpitations
- Shortness of breath
- Cold extremities
- Insomnia
Safety Measures
- Alcohol - Alcohol can lower blood pressure and may enhance the hypotensive effects of this medication. Use with caution.
- Pregnancy - Not recommended during pregnancy, especially in the second and third trimesters, due to potential fetal harm. Consult a doctor.
- Breastfeeding - Both components are excreted in breast milk. Use with caution; consult a healthcare professional.
- Liver - Use with caution in patients with hepatic impairment; dosage adjustments may be necessary, especially for metoprolol.
- Kidney - Generally safe in mild to moderate renal impairment, but caution and monitoring are advised in severe cases.
- Lung - Metoprolol should be used with caution in patients with bronchospastic diseases like asthma, as it can worsen symptoms.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |

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