MINONIL ER 65 10 S

About

MINONIL ER 65 contains Isosorbide Mononitrate, a long-acting nitrate specifically formulated as an extended-release tablet. This medication is primarily prescribed for the prevention and long-term management of angina pectoris, which is chest pain resulting from insufficient blood flow to the heart muscle in patients with coronary artery disease. Isosorbide Mononitrate works by releasing nitric oxide, a potent vasodilator, which relaxes the smooth muscles in the walls of both arteries and veins. This vasodilation reduces the heart's workload by decreasing venous return (preload) and systemic vascular resistance (afterload), thereby lowering myocardial oxygen demand and improving blood flow to ischemic areas of the heart. The extended-release mechanism ensures a sustained therapeutic effect throughout the day, providing consistent relief from angina symptoms with convenient once-daily dosing, significantly enhancing the patient's quality of life by reducing the frequency and severity of angina attacks.

Uses

• Prevention of angina pectoris
• Management of chronic stable angina
• Adjunctive therapy in heart failure
• Post-myocardial infarction management

Directions For Use

Take orally once daily in the morning, with or without food. Swallow the tablet whole; do not chew or crush.

Benefits

• Sustained angina prevention
• Convenient once-daily dosing
• Improves exercise tolerance
• Reduces frequency of angina attacks
• Enhances quality of life for angina patients
• Effective in chronic management of coronary artery disease

Side Effects

• Headache
• Dizziness
• Flushing
• Nausea
• Hypotension (low blood pressure)
• Lightheadedness
• Weakness
• Tachycardia (fast heart rate)
• Dyspepsia (indigestion)
• Skin rash
• Syncope (fainting)
• Blurred vision

Safety Measures

• Alcohol - Avoid or limit alcohol, as it can enhance the hypotensive effects of the medication and increase dizziness and lightheadedness.
• Pregnancy - Consult a doctor before use. Use only if clearly needed and potential benefits to the mother outweigh risks to the fetus.
• Breastfeeding - It is unknown if Isosorbide Mononitrate is excreted in breast milk. Use with caution and consult a healthcare provider.
• Liver - Use with caution in patients with severe liver impairment. Dose adjustment may be considered based on clinical judgment.
• Kidney - Use with caution in patients with severe renal impairment. Dose adjustment may be necessary to prevent accumulation.
• Lung - Generally safe for use in patients with lung conditions, but caution is advised in cases of severe pulmonary hypertension.

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