Temozorix 100mg Injection

About

Temozorix 100mg Injection contains temozolomide, an alkylating antineoplastic agent administered intravenously for the treatment of specific brain tumors. It functions by interfering with DNA replication and transcription, leading to cell cycle arrest and apoptosis in rapidly proliferating cancer cells. This intravenous formulation ensures rapid systemic delivery and bioavailability, making it an effective option for patients who may not tolerate oral administration or require immediate treatment.

This medication is primarily indicated for newly diagnosed glioblastoma multiforme, often used concurrently with radiotherapy and followed by adjuvant therapy. It is also prescribed for refractory anaplastic astrocytoma that has progressed despite previous treatments. Temozorix works by damaging the genetic material within tumor cells, thereby inhibiting their growth and spread, which helps in controlling disease progression and improving clinical outcomes.

Uses

• Treatment of newly diagnosed glioblastoma multiforme.
• Management of refractory anaplastic astrocytoma.
• Used in certain other malignant gliomas.
• Alternative for patients unable to take oral temozolomide.

Directions For Use

Administered intravenously by a healthcare professional. The dosage and infusion rate will be determined by your doctor.

Benefits

• Effective against specific types of brain tumors.
• Ensures rapid systemic delivery and bioavailability.
• Suitable for patients unable to take oral medication.
• Often used synergistically with radiation therapy.
• Helps to extend progression-free survival.
• Targets rapidly dividing cancer cells effectively.

Side Effects

• Nausea and vomiting
• Fatigue and weakness
• Headache
• Constipation
• Loss of appetite
• Hair loss (alopecia)
• Myelosuppression (low blood counts)
• Thrombocytopenia (low platelets)
• Neutropenia (low neutrophils)
• Anemia
• Skin rash
• Increased risk of infections

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may worsen gastrointestinal side effects or liver strain.
• Pregnancy - Contraindicated during pregnancy due to significant risk of fetal harm; use effective contraception.
• Breastfeeding - Not recommended while breastfeeding as the drug may pass into breast milk and harm the infant.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustments may be necessary.
• Kidney - Administer with caution in patients with severe renal impairment; close monitoring is advised.
• Lung - Rarely associated with interstitial pneumonitis; monitor for new or worsening respiratory symptoms.

Disclaimer

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