TENEPRIDE M 500 TAB

About

TENEPRIDE M 500 TAB is a combination medication used for the treatment of type 2 diabetes mellitus, typically containing Teneligliptin and Metformin 500mg. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the levels of incretin hormones (GLP-1 and GIP). These hormones enhance glucose-dependent insulin secretion from pancreatic beta cells and suppress glucagon secretion from alpha cells, leading to improved blood glucose control. Metformin, a biguanide, reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues. This synergistic action helps to lower both fasting and post-meal blood sugar levels, providing comprehensive glycemic management for adults with type 2 diabetes, especially when diet and exercise alone are insufficient.

Uses

• Management of type 2 diabetes mellitus.
• As an adjunct to diet and exercise.
• To improve glycemic control in adults.
• When monotherapy with metformin is insufficient.

Directions For Use

Take orally with meals, usually once or twice daily, as directed by your healthcare provider. Swallow the tablet whole with water.

Benefits

• Provides dual action for effective glycemic control.
• Low risk of hypoglycemia due to glucose-dependent action.
• Metformin component may aid in weight management.
• Improves both fasting and post-prandial glucose levels.
• Convenient fixed-dose combination.
• May offer cardiovascular benefits (Metformin).

Side Effects

• Nausea and vomiting.
• Diarrhea.
• Abdominal pain or discomfort.
• Headache.
• Upper respiratory tract infection.
• Nasopharyngitis.
• Metallic taste in mouth.
• Lactic acidosis (rare, serious).
• Pancreatitis (rare, DPP-4 inhibitors).
• Joint pain.
• Skin rash.
• Vitamin B12 deficiency (long-term use).

Safety Measures

• Alcohol - Avoid excessive alcohol consumption due to increased risk of lactic acidosis with metformin.
• Pregnancy - Not recommended during pregnancy; consult your doctor for safer alternatives.
• Breastfeeding - Not advised as components may pass into breast milk and potentially harm the infant.
• Liver - Use with caution in patients with hepatic impairment; metformin may increase the risk of lactic acidosis.
• Kidney - Contraindicated in severe renal impairment due to increased risk of lactic acidosis; dose adjustment needed for moderate impairment.
• Lung - Use with caution in severe respiratory conditions due to potential for hypoxia, which can increase lactic acidosis risk with metformin.

Disclaimer

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