About
ZITAMET PLUS 20/1000 TAB is a combination oral antidiabetic medication containing Teneligliptin 20mg and Metformin 1000mg, specifically formulated for the comprehensive management of Type 2 Diabetes Mellitus. Teneligliptin, a DPP-4 inhibitor, works by enhancing the body's natural incretin system, leading to increased glucose-dependent insulin secretion and suppressed glucagon release, thereby improving blood glucose control. Metformin, a biguanide, complements this action by reducing glucose production in the liver and improving the sensitivity of peripheral tissues to insulin, facilitating better glucose uptake and utilization.
This synergistic combination targets multiple pathophysiological defects of Type 2 diabetes, providing robust glycemic control. It is particularly beneficial for patients who have not achieved adequate blood sugar control with diet, exercise, or monotherapy with either Teneligliptin or Metformin alone. By effectively lowering both fasting and post-meal blood glucose levels, ZITAMET PLUS 20/1000 helps to significantly reduce HbA1c and mitigate the risk of long-term complications associated with uncontrolled diabetes, such as cardiovascular disease, kidney damage, and nerve problems, ultimately enhancing patient health outcomes.
Uses
- Management of Type 2 Diabetes Mellitus.
- When diet and exercise alone are insufficient.
- When monotherapy with Teneligliptin or Metformin is inadequate.
- To improve glycemic control and reduce HbA1c.
Directions For Use
Take orally with meals, usually once or twice daily, as directed by your physician. Swallow the tablet whole without crushing or chewing.
Benefits
- Provides synergistic action for robust glucose control.
- Significantly reduces HbA1c levels for long-term management.
- Low risk of hypoglycemia (due to Teneligliptin component).
- Helps prevent severe long-term diabetes complications.
- Weight neutral or potential for modest weight loss (due to Metformin).
- Convenient dosing for enhanced patient adherence.
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Metallic taste in mouth
- Lactic acidosis (rare, serious, due to Metformin)
- Headache
- Dizziness
- Nasopharyngitis (common cold symptoms)
- Pancreatitis (rare, due to Teneligliptin)
- Skin rash
- Constipation
- Vitamin B12 deficiency (long-term Metformin use)
- Dyspepsia
Safety Measures
- Alcohol - Avoid or limit alcohol consumption due to increased risk of lactic acidosis with Metformin.
- Pregnancy - Generally not recommended during pregnancy; insulin is usually preferred. Consult your doctor immediately if pregnant or planning pregnancy.
- Breastfeeding - Not recommended during breastfeeding as Metformin passes into breast milk. Consult your doctor.
- Liver - Use with caution in moderate hepatic impairment; contraindicated in severe hepatic impairment due to Metformin.
- Kidney - Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²) due to Metformin accumulation and risk of lactic acidosis.
- Lung - Use with caution in severe respiratory conditions that may predispose to hypoxia and increase the risk of lactic acidosis.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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| Shop Location | Assam, India |
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