Adstrom 50mg Tablet

About

Adstrom is a highly effective hormonal therapy, most likely an aromatase inhibitor, primarily utilized in the treatment of hormone-receptor-positive cancers, particularly breast cancer in postmenopausal women. Its mechanism of action involves selectively blocking the enzyme aromatase, which is responsible for the conversion of androgens into estrogens in peripheral tissues, including fat, muscle, and the tumor itself. In postmenopausal women, where the ovaries no longer produce significant amounts of estrogen, peripheral aromatization becomes the primary source of estrogen. By profoundly reducing systemic estrogen levels, Adstrom effectively deprives hormone-sensitive cancer cells of the estrogen they require for growth and proliferation. This targeted endocrine therapy aims to prevent the recurrence and progression of estrogen-dependent tumors, offering a crucial therapeutic strategy to improve long-term outcomes and disease-free survival in eligible patients.

Uses

• Adjuvant treatment of early breast cancer.
• Treatment of advanced breast cancer.
• Extended adjuvant therapy for breast cancer.
• Management of hormone-sensitive tumors.

Directions For Use

Take one tablet orally once daily, at approximately the same time each day, with or without food. Follow your doctor's instructions.

Benefits

• Effective in hormone-receptor-positive cancers.
• Reduces estrogen levels.
• Prevents cancer recurrence.
• Oral administration.
• Well-established efficacy in breast cancer.
• Improved disease-free survival.

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Fatigue
• Nausea
• Headache
• Bone thinning (osteoporosis)
• Vaginal dryness
• Hair thinning
• Weight gain
• Mood disturbances
• Peripheral edema
• Elevated cholesterol

Safety Measures

• Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake may worsen hot flashes or other side effects.
• Pregnancy - Contraindicated in pregnancy due to potential for fetal harm. Not typically used in premenopausal women unless specific conditions apply.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and could harm the infant.
• Liver - Use with caution in patients with liver impairment; monitor liver function and adjust dose if necessary.
• Kidney - Generally safe in patients with mild to moderate renal impairment; severe impairment may require dose adjustment.
• Lung - No specific lung-related precautions, but monitor for any new or worsening respiratory symptoms.

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