Bdron 250mg Tablet

About

Bdron 250mg Tablet is an anti-arrhythmic agent used for the long-term management and prevention of various cardiac arrhythmias. As a Class III anti-arrhythmic, it primarily functions by prolonging the repolarization phase of the cardiac action potential through the blockade of potassium channels. This action increases the effective refractory period of the heart muscle, thereby stabilizing abnormal electrical activity. In addition to its potassium channel blocking effects, it also exhibits mild non-competitive alpha- and beta-adrenergic blocking properties, and some sodium and calcium channel antagonism, contributing to its broad anti-arrhythmic efficacy.

This medication is often used as a maintenance dose after initial loading with higher doses, or for less severe but persistent arrhythmias. Its ability to regulate heart rhythm helps to prevent dangerous episodes of tachycardia and fibrillation, improving cardiac function and reducing the risk of arrhythmia-related complications. Due to its complex pharmacokinetics and potential for systemic side effects, close monitoring by a healthcare professional is essential during treatment.

Uses

• Long-term maintenance of sinus rhythm in atrial fibrillation.
• Prevention of recurrent ventricular tachycardia.
• Management of other chronic supraventricular arrhythmias.
• Adjunctive therapy for severe, refractory arrhythmias.

Directions For Use

Take orally as directed by your cardiologist, usually once daily with food. Do not discontinue without medical advice.

Benefits

• Effective for long-term arrhythmia control.
• Helps maintain stable heart rhythm.
• Reduces recurrence of atrial fibrillation.
• Prevents life-threatening ventricular arrhythmias.
• Improves cardiac function.
• Reduces symptoms like palpitations and dizziness.

Side Effects

• Nausea
• Vomiting
• Constipation
• Tremor
• Dizziness
• Fatigue
• Photosensitivity
• Corneal microdeposits
• Thyroid dysfunction (hypo/hyperthyroidism)
• Pulmonary toxicity (fibrosis)
• Liver enzyme elevation
• Bradycardia

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can exacerbate liver toxicity and potentially interact with the medication's effects on the heart.
• Pregnancy - Contraindicated during pregnancy due to significant risk of fetal harm, including thyroid abnormalities; use only if life-threatening and no safer alternative exists.
• Breastfeeding - Not recommended during breastfeeding as it is excreted into breast milk and can cause serious adverse effects in the infant, including thyroid dysfunction.
• Liver - Use with extreme caution in patients with liver disease; regular monitoring of liver function tests is essential due to risk of hepatotoxicity.
• Kidney - Generally safe for use in patients with kidney conditions; no dose adjustment typically required, but monitor for overall systemic effects.
• Lung - Contraindicated or used with extreme caution in patients with pre-existing lung disease due to the significant risk of severe and potentially fatal pulmonary toxicity (e.g., pulmonary fibrosis).

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