DAPARYL 10

About

DAPARYL 10 contains Dapagliflozin 10mg, an oral antidiabetic medication belonging to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors. This medication works by blocking the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine. This mechanism results in a reduction of blood glucose levels independently of insulin secretion. Beyond its glucose-lowering effects, Dapagliflozin has demonstrated significant cardiovascular and renal benefits, making it a valuable treatment option for patients with type 2 diabetes, heart failure with reduced ejection fraction, and chronic kidney disease. It helps to improve glycemic control, reduce body weight, and lower blood pressure, contributing to a comprehensive management strategy for these interconnected conditions.

Uses

• Management of type 2 diabetes mellitus
• Treatment of heart failure with reduced ejection fraction
• Management of chronic kidney disease
• Aids in reducing cardiovascular risk in diabetic patients

Directions For Use

Take orally once daily in the morning, with or without food, as directed by your physician. Swallow the tablet whole with water.

Benefits

• Effectively lowers blood glucose and HbA1c levels
• Promotes modest weight loss
• Contributes to lower blood pressure
• Reduces the risk of cardiovascular events
• Slows the progression of chronic kidney disease
• Provides a convenient once-daily dosage

Side Effects

• Genital mycotic infections (e.g., yeast infections)
• Urinary tract infections (UTIs)
• Increased urination (polyuria)
• Increased thirst
• Dizziness
• Hypotension (low blood pressure)
• Diabetic ketoacidosis (rare but serious)
• Acute kidney injury (rare)
• Allergic reactions
• Back pain
• Dyslipidemia (abnormal lipid levels)
• Hypoglycemia (when combined with other antidiabetics)

Safety Measures

• Alcohol - Limit or avoid alcohol consumption as it can increase the risk of dehydration and diabetic ketoacidosis.
• Pregnancy - Not recommended during pregnancy. Consult your doctor immediately if you are pregnant or planning to conceive.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk. Consult your doctor.
• Liver - Use with caution in patients with severe hepatic impairment. Dose adjustment may be considered.
• Kidney - Not recommended in severe renal impairment (eGFR <25 mL/min/1.73 m²). Regular monitoring of kidney function is essential.
• Lung - No specific lung-related safety concerns, but caution in patients with severe respiratory conditions due to potential for dehydration.

Disclaimer

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