VILATIN SR 100 15

About

VILATIN SR 100 contains Vildagliptin in a sustained-release formulation, indicated for the treatment of type 2 diabetes mellitus in adults. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by enhancing the body's natural ability to control blood glucose levels. It achieves this by increasing the levels of active incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones stimulate insulin release from the pancreas in a glucose-dependent manner and suppress glucagon secretion from the alpha cells.

The sustained-release formulation of Vildagliptin 100mg allows for once-daily dosing, providing consistent and prolonged glycemic control throughout the day. This helps to reduce both fasting and post-meal blood sugar levels, contributing to a significant reduction in HbA1c. Vildagliptin is often used as an adjunct to diet and exercise, either as monotherapy or in combination with other antidiabetic agents, when initial treatment fails to achieve adequate glycemic targets.

Uses

• Treatment of type 2 diabetes mellitus
• Improvement of glycemic control
• Enhancement of glucose-dependent insulin secretion
• Suppression of glucagon release

Directions For Use

Take orally once daily in the morning, with or without food. Swallow the tablet whole; do not crush or chew.

Benefits

• Effective blood sugar control with once-daily dosing
• Low risk of hypoglycemia (as monotherapy)
• Improves both fasting and post-meal glucose levels
• Enhances pancreatic beta-cell function
• Generally weight neutral
• Well-tolerated with a favorable safety profile

Side Effects

• Nasopharyngitis
• Headache
• Dizziness
• Tremor
• Fatigue
• Constipation
• Peripheral edema
• Pancreatitis (rare, serious)
• Liver enzyme elevation (rare)
• Skin reactions (e.g., rash)
• Joint pain
• Hypoglycemia (when combined with sulfonylureas/insulin)

Safety Measures

• Alcohol - Moderate alcohol intake is generally acceptable, but excessive use should be avoided as it may affect blood sugar levels.
• Pregnancy - Not recommended during pregnancy. Consult your doctor for appropriate diabetes management during this period.
• Breastfeeding - Not advised as there is a potential for adverse effects in breastfed infants. Discuss alternatives with your doctor.
• Liver - Not recommended for patients with hepatic impairment, including those with elevated liver enzymes (ALT or AST >3x ULN).
• Kidney - Use with caution in moderate to severe renal impairment; dosage adjustment may be required based on eGFR.
• Lung - Generally safe for patients with lung conditions; no specific lung-related contraindications are known.

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