About
Entecavir is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection in adults and children aged 2 years and older. It belongs to a class of drugs called nucleoside analogues. Entecavir works by inhibiting the HBV reverse transcriptase, an enzyme essential for the virus to replicate its genetic material. This action significantly reduces the viral load in the body, thereby decreasing liver inflammation and preventing further liver damage, such as cirrhosis and liver cancer.
It is particularly effective in patients with evidence of active viral replication and persistent elevations in serum aminotransferases or histological evidence of active disease. Treatment with entecavir helps to improve liver function and reduce the risk of long-term complications associated with chronic HBV, offering a crucial intervention for managing this persistent viral infection.
Uses
- Treatment of chronic hepatitis B virus (HBV) infection.
- Reduction of HBV viral load.
- Prevention of liver damage due to HBV.
- Improvement of liver function in HBV patients.
Directions For Use
Take orally once daily on an empty stomach (at least 2 hours after and 2 hours before a meal). Follow your doctor's prescribed dosage and duration.
Benefits
- Effectively suppresses hepatitis B virus replication.
- Reduces the risk of liver cirrhosis and liver cancer.
- Improves liver enzyme levels.
- Well-tolerated by most patients.
- Available in convenient once-daily dosing.
- Helps prevent disease progression in chronic HBV.
Side Effects
- Headache
- Fatigue
- Dizziness
- Nausea
- Diarrhea
- Abdominal pain
- Insomnia
- Increased liver enzymes
- Lactic acidosis (rare but serious)
- Renal impairment (rare)
- Rash
- Peripheral neuropathy
Safety Measures
- Alcohol - Avoid or limit alcohol consumption as it can worsen liver disease and potentially increase the risk of side effects.
- Pregnancy - Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.
- Breastfeeding - It is generally not recommended due to potential excretion into breast milk. Discuss with your healthcare provider.
- Liver - Use with caution in patients with pre-existing liver conditions; regular monitoring of liver function is essential.
- Kidney - Dosage adjustment is required for patients with impaired kidney function. Close monitoring is necessary.
- Lung - No specific contraindications or precautions related to lung conditions are generally noted for this medication.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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