JUPIROS F 10

About

This medication is a combination therapy designed to address multiple lipid abnormalities, typically comprising a statin (HMG-CoA reductase inhibitor) and a fibrate (PPARα agonist). The statin component works by reducing the liver's production of cholesterol, primarily lowering low-density lipoprotein cholesterol (LDL-C) and total cholesterol, while also having a modest effect on triglycerides and high-density lipoprotein cholesterol (HDL-C). The fibrate component primarily targets high triglycerides by increasing their breakdown and removal from the blood, and also significantly raises HDL-C.

This dual mechanism of action provides comprehensive lipid management, making it particularly effective for patients with mixed dyslipidemia, where both high cholesterol and high triglycerides are present. It aims to reduce the overall risk of cardiovascular events such as heart attacks and strokes by improving the lipid profile more extensively than either agent alone.

Uses

• Treatment of mixed dyslipidemia
• Management of severe hypertriglyceridemia with elevated LDL-C
• Patients requiring comprehensive lipid management
• Prevention of cardiovascular events in high-risk individuals

Directions For Use

Take one tablet orally once daily, preferably with food, or as advised by your healthcare provider.

Benefits

• Provides comprehensive lipid management
• Significantly lowers LDL ("bad") cholesterol
• Effectively reduces high triglycerides
• Increases "good" HDL cholesterol
• Reduces the risk of cardiovascular events
• Convenient single-pill therapy for multiple lipid issues

Side Effects

• Muscle pain (myalgia)
• Abdominal pain
• Nausea
• Headache
• Elevated liver enzymes
• Gallstones
• Rhabdomyolysis (rare, severe muscle breakdown)
• Pancreatitis (rare)
• Fatigue
• Diarrhea
• Constipation
• Joint pain

Safety Measures

• Alcohol - Limit alcohol intake, as it can increase the risk of liver problems and myopathy, which are potential side effects of both components.
• Pregnancy - Contraindicated during pregnancy (Category X) due to potential harm to the fetus. Do not use if pregnant or planning pregnancy.
• Breastfeeding - Contraindicated during breastfeeding as components may pass into breast milk and harm the infant.
• Liver - Contraindicated in patients with active liver disease or unexplained persistent elevations in liver transaminases. Monitor liver function tests closely.
• Kidney - Contraindicated in patients with severe renal impairment. Dose adjustment is necessary for moderate renal impairment.
• Lung - No specific contraindications or precautions related to lung conditions are generally noted for this combination.

Disclaimer

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