RAZEL F 10 FORTE 10 S

About

RAZEL F 10 FORTE combines Rosuvastatin, a potent HMG-CoA reductase inhibitor (statin), and Fenofibrate, a fibric acid derivative. Rosuvastatin primarily works by reducing the production of cholesterol in the liver, thereby lowering LDL-C ("bad" cholesterol) and triglycerides, and increasing HDL-C ("good" cholesterol). Fenofibrate primarily acts by activating peroxisome proliferator-activated receptor alpha (PPARα), which leads to increased breakdown of triglycerides and removal of triglyceride-rich particles from the blood, as well as a modest increase in HDL-C. This combination therapy is particularly effective in patients with mixed dyslipidemia, where both elevated cholesterol and triglycerides are present, and who have not achieved target lipid levels with monotherapy. It helps to reduce the risk of cardiovascular events by improving the overall lipid profile and managing lipid abnormalities comprehensively.

Uses

• Treatment of mixed dyslipidemia.
• Reduction of elevated total cholesterol and LDL-C.
• Lowering of high triglyceride levels.
• Increasing HDL-C in patients with dyslipidemia.

Directions For Use

Take this medication orally, usually once daily with or without food, as directed by your physician. Do not crush or chew the tablet.

Benefits

• Comprehensive lipid profile improvement.
• Significant reduction in LDL-C and triglycerides.
• Increased levels of protective HDL-C.
• Reduced risk of atherosclerotic cardiovascular disease.
• Convenient single-pill combination therapy.
• Effective for patients with mixed dyslipidemia.

Side Effects

• Muscle pain or weakness (myalgia)
• Headache
• Nausea
• Abdominal pain
• Diarrhea
• Constipation
• Dizziness
• Elevated liver enzymes
• Pancreatitis (rare)
• Gallstones (rare)
• Rash
• Fatigue

Safety Measures

• Alcohol - Excessive alcohol consumption may increase the risk of liver problems and muscle side effects when taking this medication. Limit alcohol intake.
• Pregnancy - This medication is contraindicated during pregnancy due to potential harm to the fetus. Use effective contraception.
• Breastfeeding - It is not recommended during breastfeeding as it may pass into breast milk and harm the infant. Consult your doctor.
• Liver - Use with caution in patients with pre-existing liver disease. Regular liver function tests are necessary. Contraindicated in active liver disease.
• Kidney - Dose adjustment may be required in patients with moderate to severe kidney impairment. Monitor kidney function closely.
• Lung - Generally safe for use in patients with lung conditions, but report any new or worsening respiratory symptoms to your doctor.

Disclaimer

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