About
Lanoxin tablets contain Digoxin, a cardiac glycoside primarily used in the management of heart failure with reduced ejection fraction (HFrEF) and for rate control in atrial fibrillation. Digoxin works by inhibiting the Na+/K+-ATPase pump in cardiac muscle cells, leading to an increase in intracellular calcium. This results in a positive inotropic effect, meaning it strengthens the force of myocardial contraction, thereby improving the heart's pumping efficiency. Additionally, Digoxin slows the heart rate by increasing vagal tone and decreasing conduction through the AV node, which is beneficial in controlling ventricular rate in atrial fibrillation.
Due to its narrow therapeutic index, careful dosing and monitoring of serum digoxin levels are crucial to avoid toxicity. It helps to alleviate symptoms of heart failure, such as shortness of breath and edema, and can improve exercise tolerance. Despite newer therapies, Digoxin remains a valuable medication for specific cardiac conditions, particularly when symptom control is paramount.
Uses
- Treatment of chronic heart failure (HFrEF).
- Rate control in chronic atrial fibrillation.
- Management of atrial flutter.
- Treatment of certain supraventricular tachycardias.
Directions For Use
Take orally once daily, with precise dosing based on patient factors and serum levels, as directed by your physician.
Benefits
- Improves cardiac contractility and pumping efficiency.
- Slows down rapid heart rates in atrial fibrillation.
- Reduces symptoms of heart failure like dyspnea and edema.
- Increases exercise tolerance in heart failure patients.
- May reduce hospitalizations for heart failure.
- Provides symptomatic relief for chronic cardiac conditions.
Side Effects
- Nausea
- Vomiting
- Anorexia
- Diarrhea
- Visual disturbances (yellow/green halos)
- Bradycardia
- Heart block
- Ventricular arrhythmias
- Fatigue
- Confusion
- Dizziness
- Headache
Safety Measures
- Alcohol - No direct interaction, but excessive alcohol can worsen underlying cardiac conditions. Moderate intake is advised.
- Pregnancy - Use only if clearly needed and potential benefits outweigh risks. Digoxin crosses the placenta, and fetal monitoring is recommended.
- Breastfeeding - Digoxin is excreted in breast milk. Use with caution, and monitor the infant for signs of toxicity. Consult your doctor.
- Liver - Dose adjustment is usually not needed as Digoxin is primarily renally cleared, but monitor for adverse effects in severe liver disease.
- Kidney - Significant dose reduction is required in renal impairment. Monitor kidney function and serum digoxin levels closely to prevent toxicity.
- Lung - Generally safe for lung conditions, but monitor for hypoxia which can increase sensitivity to Digoxin's effects.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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