NULONG T TAB

About

NULONG T TAB is a dual-component medication specifically designed for the effective treatment of essential hypertension, particularly when monotherapy with either Telmisartan or Hydrochlorothiazide alone proves insufficient. It combines Telmisartan, an angiotensin II receptor blocker (ARB), with Hydrochlorothiazide, a thiazide diuretic. Telmisartan exerts its antihypertensive effect by selectively blocking the AT1 receptor, which prevents the binding of angiotensin II and subsequently inhibits its vasoconstrictive and aldosterone-secreting actions. This leads to effective vasodilation and a reduction in peripheral vascular resistance. Hydrochlorothiazide complements this action by increasing the renal excretion of sodium and water, thereby reducing plasma volume and further lowering blood pressure. This synergistic mechanism of action provides additive antihypertensive effects, allowing for more efficient and sustained blood pressure control. The combination helps to achieve target blood pressure levels more effectively, thereby reducing the overall cardiovascular risk associated with uncontrolled hypertension.

Uses

• Treatment of essential hypertension.
• When monotherapy with Telmisartan or Hydrochlorothiazide is insufficient.
• Reduction of cardiovascular risk in high-risk patients.
• Management of fluid retention associated with hypertension.

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your physician.

Benefits

• Effective and sustained blood pressure reduction.
• Combines two complementary antihypertensive mechanisms.
• Reduces the risk of stroke and heart attack.
• Convenient once-daily dosing.
• May help manage mild fluid retention.
• Generally well-tolerated.

Side Effects

• Dizziness
• Headache
• Fatigue
• Nausea
• Diarrhea
• Hypotension
• Hyperkalemia (Telmisartan)
• Hypokalemia (Hydrochlorothiazide)
• Muscle cramps
• Increased urination
• Gout exacerbation (Hydrochlorothiazide)
• Upper respiratory tract infection

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it may increase the hypotensive effect and risk of dizziness.
• Pregnancy - Contraindicated during pregnancy, especially in the second and third trimesters, due to risk of fetal harm.
• Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk and affect the infant.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be necessary.
• Kidney - Contraindicated in anuria; use with caution and monitor function in severe renal impairment.
• Lung - Generally safe for use in patients with lung conditions; does not typically cause respiratory issues.

Disclaimer

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