PRICHAK M-1 10 S

About

PRICHAK M-1 contains Metformin, an oral antidiabetic medication belonging to the biguanide class, primarily used for the management of type 2 diabetes mellitus. Metformin works by several mechanisms to lower blood glucose levels. Its main action is to reduce glucose production by the liver, a process known as hepatic gluconeogenesis. Additionally, it improves insulin sensitivity in peripheral tissues, such as muscle and fat cells, allowing them to absorb and utilize glucose more effectively from the bloodstream. Metformin also decreases the absorption of glucose from the gastrointestinal tract.

Unlike some other antidiabetic agents, Metformin does not typically cause weight gain and has a lower risk of hypoglycemia when used as monotherapy. It is often the first-line treatment for type 2 diabetes, especially in overweight or obese patients, and is used as an adjunct to diet and exercise to achieve optimal glycemic control and reduce the long-term complications associated with diabetes.

Uses

• Management of type 2 diabetes mellitus.
• To improve glycemic control in adults.
• Used as an adjunct to diet and exercise.
• May be used in prediabetes to prevent progression.

Directions For Use

Take this medicine orally with food, as directed by your physician. Swallow the tablet whole with a glass of water.

Benefits

• Effective blood sugar control.
• Reduces hepatic glucose production.
• Improves insulin sensitivity.
• Does not typically cause weight gain.
• Lower risk of hypoglycemia (when used alone).
• Reduces risk of cardiovascular events in some patients.

Side Effects

• Nausea
• Diarrhea
• Abdominal pain
• Vomiting
• Metallic taste
• Loss of appetite
• Headache
• Dizziness
• Lactic acidosis (rare but serious)
• Vitamin B12 deficiency
• Flatulence
• Weakness

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it can significantly increase the risk of lactic acidosis, a rare but serious side effect of Metformin.
• Pregnancy - Consult your doctor. While Metformin may be used in some cases of gestational diabetes, insulin is generally preferred.
• Breastfeeding - Small amounts of Metformin may pass into breast milk. Consult your doctor to weigh the benefits and risks for the infant.
• Liver - Use with caution in patients with liver impairment, as it can increase the risk of lactic acidosis. Not recommended in severe liver disease.
• Kidney - Contraindicated in severe kidney impairment (eGFR <30 mL/min/1.73m²) due to increased risk of lactic acidosis. Dose adjustment is required for moderate impairment.
• Lung - Generally safe for use in patients with stable lung conditions. However, severe respiratory conditions leading to hypoxia can increase lactic acidosis risk.

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