RECLIMET OD 30

About

RECLIMET OD 30 is a combination medication specifically formulated for the management of Type 2 Diabetes Mellitus. It combines two potent antidiabetic agents: Gliclazide, a sulfonylurea, and Metformin, a biguanide. Gliclazide works primarily by stimulating the pancreatic beta cells to release more insulin, thereby lowering blood glucose levels. Metformin, on the other hand, acts by reducing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity in peripheral tissues. This dual mechanism of action provides comprehensive glycemic control, addressing both insulin secretion and insulin resistance, which are key pathophysiological defects in Type 2 Diabetes. The extended-release (OD) formulation ensures sustained therapeutic effects, contributing to better adherence and stable blood sugar management throughout the day. This combination is particularly beneficial for patients whose blood sugar is not adequately controlled by monotherapy.

Uses

• Management of Type 2 Diabetes Mellitus.
• Improvement of glycemic control.
• Reduction of fasting and post-prandial blood sugar levels.
• Prevention of diabetes-related complications.

Directions For Use

Take as directed by your physician, usually with meals to minimize gastrointestinal upset and improve absorption.

Benefits

• Effective blood sugar control.
• Dual mechanism of action.
• Reduced risk of hyperglycemia.
• Improved insulin sensitivity.
• Potential for weight management (Metformin).
• Convenient once-daily dosing (OD).

Side Effects

• Hypoglycemia (low blood sugar)
• Nausea
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Metallic taste
• Lactic acidosis (rare, serious)
• Skin rash
• Weight gain (Gliclazide)
• Vitamin B12 deficiency (long-term Metformin)
• Flatulence

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis.
• Pregnancy - Generally not recommended; consult a doctor as insulin may be preferred for glycemic control during pregnancy.
• Breastfeeding - Not recommended; consult a doctor as the components may pass into breast milk.
• Liver - Use with caution; severe liver impairment increases the risk of lactic acidosis and hypoglycemia.
• Kidney - Contraindicated in severe renal impairment due to increased risk of lactic acidosis (Metformin) and drug accumulation.
• Lung - Use with caution in severe respiratory conditions that may predispose to hypoxia and lactic acidosis.

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