Revolade 25mg Tablet

About

Revolade 25mg Tablet contains Eltrombopag, a potent, orally active thrombopoietin receptor agonist. This medication functions by selectively binding to and activating the thrombopoietin receptor on the surface of hematopoietic stem cells and megakaryocyte progenitor cells in the bone marrow. This activation stimulates the proliferation and differentiation of megakaryocytes, which are the precursor cells responsible for producing platelets. The ultimate effect is a significant and sustained increase in the production of platelets, thereby elevating the platelet count in the peripheral blood. It is primarily indicated for the management of conditions characterized by critically low platelet counts, such as chronic immune thrombocytopenia (ITP) and severe aplastic anemia, where the risk of bleeding is substantial. The therapeutic objective is to achieve and maintain a platelet count sufficient to minimize or prevent clinically significant hemorrhagic events, improving patient safety and quality of life.

Uses

• Treatment of chronic immune thrombocytopenia (ITP) in adults and children.
• Treatment of severe aplastic anemia (SAA) in patients refractory to immunosuppressive therapy.
• Treatment of thrombocytopenia in patients with chronic hepatitis C virus (HCV) infection.
• Management of low platelet counts to reduce the need for platelet transfusions.

Directions For Use

Take this tablet orally, usually once daily, with or without food. Follow your doctor's prescribed dosage and duration.

Benefits

• Significantly increases platelet count.
• Reduces the risk of bleeding episodes.
• Decreases the need for platelet transfusions.
• Improves quality of life for patients with chronic ITP.
• Offers a non-immunosuppressive option for SAA.
• Helps manage thrombocytopenia in HCV patients.

Side Effects

• Nausea
• Diarrhea
• Upper respiratory tract infection
• Fatigue
• Headache
• Muscle pain
• Abdominal pain
• Cough
• Fever
• Increased liver enzymes
• Cataracts
• Thromboembolic events

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it may exacerbate liver issues, which can be a concern with this medication.
• Pregnancy - Generally not recommended during pregnancy unless the potential benefit outweighs the risk. Consult a doctor.
• Breastfeeding - It is advised to avoid breastfeeding while on this medication due to potential harm to the infant.
• Liver - Use with caution in patients with pre-existing liver impairment; dose adjustments and close monitoring of liver function are often required.
• Kidney - Generally considered safe for use in patients with kidney conditions, but monitoring is advisable.
• Lung - No specific contraindications related to lung conditions, but overall health should be assessed.

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