DAPARYL 5MG 10'S

About

DAPARYL 5MG contains Dapagliflozin, an oral antidiabetic medication classified as a sodium-glucose co-transporter 2 (SGLT2) inhibitor. Its primary mechanism involves inhibiting SGLT2 in the renal tubules, which reduces glucose reabsorption and increases glucose excretion in the urine. This leads to a reduction in blood glucose levels, independent of insulin secretion. Dapagliflozin is a valuable treatment option for type 2 diabetes mellitus, either as monotherapy or in combination with other antidiabetic agents.

Beyond its glucose-lowering effects, Dapagliflozin has demonstrated significant benefits in reducing the risk of cardiovascular events, hospitalization for heart failure, and progression of chronic kidney disease. It also contributes to modest weight loss and blood pressure reduction, offering a comprehensive approach to managing diabetes and its associated comorbidities.

Uses

• Management of type 2 diabetes mellitus
• Reduction of cardiovascular risk in type 2 diabetes patients with established cardiovascular disease
• Reduction of hospitalization for heart failure
• Management of chronic kidney disease

Directions For Use

Take orally once daily, with or without food, as directed by your physician.

Benefits

• Effectively lowers blood glucose levels
• Promotes modest weight loss
• Reduces blood pressure
• Provides cardiovascular protection
• Offers renal protective effects
• Reduces risk of hospitalization for heart failure

Side Effects

• Urinary tract infections (UTIs)
• Genital yeast infections
• Increased urination
• Thirst
• Dizziness
• Low blood pressure (hypotension)
• Ketoacidosis (rare)
• Kidney problems
• Back pain
• Nausea
• Constipation
• Fournier's gangrene (very rare)

Safety Measures

• Alcohol - Alcohol consumption may increase the risk of dehydration and, if combined with other medications like metformin, the risk of lactic acidosis. Use with caution.
• Pregnancy - Not recommended during pregnancy, especially in the second and third trimesters, due to potential adverse effects on fetal kidney development. Consult your doctor.
• Breastfeeding - It is not recommended during breastfeeding as it may pass into breast milk and affect the infant. Consult your doctor.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be necessary.
• Kidney - Contraindicated in patients with severe renal impairment (eGFR < 30 mL/min/1.73m²). Regular monitoring of kidney function is essential.
• Lung - Generally no direct lung effects. However, monitor for fluid status, as severe dehydration could indirectly impact respiratory function.

Disclaimer

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