Diti REV D Capsule

About

Diti REV D Capsule is a combination medication designed to address gastrointestinal issues by combining a proton pump inhibitor (PPI) with a prokinetic agent. Rabeprazole, the PPI component, works by irreversibly binding to and inhibiting the H+/K+-ATPase enzyme system (the proton pump) in gastric parietal cells, thereby significantly reducing gastric acid secretion. Domperidone, the prokinetic component, acts as a dopamine receptor antagonist, primarily at the D2 receptors, to enhance gastrointestinal motility and accelerate gastric emptying without affecting gastric acid secretion. This dual action effectively alleviates symptoms associated with acid reflux and impaired gut motility, promoting healing of esophageal erosions and ulcers.

Uses

• Treatment of Gastroesophageal Reflux Disease (GERD)
• Management of peptic ulcer disease
• Relief from symptoms of dyspepsia (indigestion)
• Prevention of nausea and vomiting associated with acid reflux

Directions For Use

Take one capsule orally, usually once daily, preferably before a meal. Swallow the capsule whole; do not chew or crush.

Benefits

• Provides effective relief from heartburn and acid reflux
• Accelerates gastric emptying and reduces bloating
• Promotes healing of esophageal and gastric ulcers
• Reduces symptoms of nausea and vomiting
• Offers convenient dual-action therapy
• Improves overall digestive comfort

Side Effects

• Headache
• Diarrhea
• Abdominal pain
• Dry mouth
• Flatulence
• Dizziness
• Skin rash
• Weakness or fatigue
• Constipation
• Insomnia
• Breast tenderness or enlargement (gynecomastia)
• QT prolongation (rare, with domperidone)

Safety Measures

• Alcohol - Alcohol may irritate the stomach lining and exacerbate acid reflux symptoms, potentially counteracting the medication's effects. Moderate consumption is advised.
• Pregnancy - Use with caution during pregnancy and only if clearly needed, after consulting a doctor. Potential risks versus benefits should be carefully weighed.
• Breastfeeding - Domperidone is excreted in breast milk and may pose a risk to the infant. Breastfeeding is generally not recommended while taking this medication.
• Liver - Patients with moderate to severe hepatic impairment should use this medication with caution, as dose adjustments may be necessary.
• Kidney - Generally considered safe for use in patients with kidney conditions, but caution is advised in severe renal impairment.
• Lung - No direct significant adverse effects on lung function are typically associated with this medication. However, any new respiratory symptoms should be evaluated.

Disclaimer

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