Pirfetab 200mg Tablet

About

Pirfenidone, the active ingredient in Pirfetab 200mg Tablet, is an antifibrotic agent primarily used in the management of idiopathic pulmonary fibrosis (IPF). IPF is a chronic, progressive, and often fatal lung disease characterized by the relentless scarring of lung tissue, leading to impaired lung function. While its precise mechanism of action is not fully elucidated, pirfenidone is believed to exert its therapeutic effects by inhibiting the synthesis of pro-fibrotic cytokines and reducing the proliferation of fibroblasts, key cellular processes involved in the pathogenesis of fibrosis.

Clinical evidence supports the use of pirfenidone in slowing the decline of lung function, as measured by forced vital capacity (FVC), and reducing the risk of acute exacerbations in patients with mild to moderate IPF. Treatment with pirfenidone requires careful medical supervision, including regular monitoring of liver function tests, due to potential adverse effects. It represents a significant therapeutic option in the comprehensive care strategy for individuals living with this challenging condition.

Uses

• Treatment of idiopathic pulmonary fibrosis (IPF).
• Slowing the progression of lung function decline in IPF.
• Reducing the risk of acute exacerbations in IPF patients.
• Managing symptoms associated with lung scarring.

Directions For Use

Take this medication orally with food, as directed by your physician, usually three times a day. Swallow the tablet whole; do not crush or chew.

Benefits

• Slows the progression of idiopathic pulmonary fibrosis.
• Helps preserve lung function over time.
• Reduces the frequency of acute IPF exacerbations.
• May improve exercise tolerance in some patients.
• Offers a targeted therapy for a severe lung disease.
• Contributes to better long-term disease management.

Side Effects

• Nausea
• Diarrhea
• Dyspepsia
• Abdominal pain
• Fatigue
• Headache
• Dizziness
• Rash
• Photosensitivity reaction
• Anorexia
• Insomnia
• Elevated liver enzymes

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may increase the risk of liver damage, a potential side effect of this medication.
• Pregnancy - Not recommended during pregnancy due to potential risks to the fetus. Consult your doctor if you are pregnant or planning to conceive.
• Breastfeeding - It is unknown if this medication passes into breast milk. Breastfeeding is generally not recommended during treatment.
• Liver - Use with caution in patients with mild to moderate liver impairment. Contraindicated in severe liver disease due to increased risk of adverse effects.
• Kidney - Use with caution in patients with mild to moderate kidney impairment. Dosage adjustments may be necessary; contraindicated in severe renal disease.
• Lung - This medication is specifically for lung fibrosis. Continue regular monitoring of lung function as advised by your specialist.

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