PRICHEK-M 2MG 10'S

About

PRICHEK-M 2MG is a combination oral antidiabetic medication containing Glimepiride (2mg) and Metformin, used for the management of type 2 diabetes mellitus. Glimepiride, a sulfonylurea, stimulates insulin release from pancreatic beta cells, thereby lowering blood glucose levels. Metformin, a biguanide, reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues, allowing the body to use insulin more effectively. This dual mechanism of action provides comprehensive blood sugar control.

This combination therapy is particularly effective for patients whose blood sugar is not adequately controlled by monotherapy with either glimepiride or metformin, or by diet and exercise alone. It helps to achieve target blood sugar levels, reduce HbA1c, and mitigate the risk of long-term diabetes complications by addressing both insulin secretion and insulin resistance.

Uses

• Treatment of type 2 diabetes mellitus.
• To improve glycemic control.
• When diet and exercise are insufficient.
• As a second-line therapy.

Directions For Use

Take orally with meals, usually once or twice daily, as directed by your physician.

Benefits

• Potent blood glucose reduction.
• Dual action for comprehensive control.
• Reduces risk of long-term diabetes complications.
• Improves insulin utilization.
• Convenient fixed-dose combination.
• Helps achieve target HbA1c levels.

Side Effects

• Hypoglycemia (low blood sugar)
• Nausea
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Metallic taste (metformin)
• Skin rash
• Weight gain (glimepiride)
• Lactic acidosis (rare, metformin)
• Vitamin B12 deficiency (metformin)
• Allergic reactions

Safety Measures

• Alcohol - Avoid or limit alcohol due to increased risk of hypoglycemia (glimepiride) and lactic acidosis (metformin).
• Pregnancy - Not recommended during pregnancy; consult a doctor for alternatives.
• Breastfeeding - Not advised during breastfeeding; seek medical guidance.
• Liver - Contraindicated in severe liver impairment due to metformin and glimepiride metabolism.
• Kidney - Contraindicated in severe kidney impairment; dose adjustment needed for moderate impairment.
• Lung - Use with caution in severe respiratory conditions due to potential for lactic acidosis.

Disclaimer

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