Sigrima 420mg Injection

Salt Composition: Pertuzumab  
Manufacturer: ZYDUS CADILA  
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MRP
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79,995
Price
:
60,500
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19,495 (24%)
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About

Sigrima 420mg Injection is a targeted therapy that contains the active ingredients pertuzumab and trastuzumab. It is prescribed to treat HER2-positive breast cancer—a type of cancer characterized by overexpression of the human epidermal growth factor receptor 2. This medication is used when the cancer has spread to other parts of the body (metastatic breast cancer) or has returned after previous treatment. It may also be administered before or after surgery in cases where the cancer has not yet metastasized. Breast cancer develops when cells grow uncontrollably and abnormally.

Before starting treatment with Sigrima 420mg Injection, inform your doctor if you have any heart conditions, a history of radiotherapy, or known allergies. This medicine is not recommended for children and adolescents under 18 years of age. In patients with early-stage HER2-positive breast cancer, the addition of pertuzumab or trastuzumab to standard chemotherapy has been shown to lower the risk of cancer recurrence and improve disease-free survival.

 Uses 

  • Breast cancer
  • Non-small cell lung cancer

Directions for use

This medicine should be administered by a doctor or nurse. Please do not attempt to self-administer it.


Side effects 
    

  • Immune system effects
  • Severe allergic reactions
  • Gastrointestinal perforation (rare)
  • Reduced blood platelets or white blood cell counts
  • Rash or itching
  • Muscle pain or weakness
  • Headache
  • Difficulty sleeping
  • Loss of appetite
  • Pulmonary toxicity (interstitial lung disease or pneumonitis)
  • Infusion-related reactions
  • Hypersensitivity reactions
  • Liver toxicity
  • Nausea and vomiting
  • Diarrhea
  • Fatigue
  • Hair loss

    
Safety Measures

Alcohol - Alcohol can impair the immune system, and individuals receiving Sigrima 420mg Injection may already have weakened immunity due to their condition or ongoing treatment. As a result, it is generally advised to limit or avoid alcohol consumption while undergoing therapy with this medication.
Pregnancy - Sigrima 420mg Injection can potentially harm the developing fetus and is therefore not considered safe for use during pregnancy.
Breastfeeding - It is not known whether Sigrima 420mg Injection passes into breast milk; therefore, breastfeeding women should consult their doctor before using this medication.
Liver - Patients with existing liver conditions or impaired liver function may have a higher risk of experiencing side effects, including liver toxicity, from Sigrima 420mg Injection. It is important to discuss your liver health with your healthcare provider before starting this medication.
Kidney - The effects of Sigrima 420mg Injection on the kidneys are not well established. Consult your doctor if you have any kidney-related concerns before starting the treatment.

  Disclaimer

Med E Hub is committed to delivering reliable, expert-reviewed information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient reilationshp.

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Shop Location Assam, India

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