Buselin 0.5mg Injection

About

Buselin 0.5mg Injection likely contains Buserelin, a synthetic analogue of gonadotropin-releasing hormone (GnRH). It acts as a potent agonist at GnRH receptors in the pituitary gland. Initially, it causes a transient surge in luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. However, with continuous administration, it leads to the desensitization and downregulation of these receptors, resulting in a profound suppression of LH and FSH release.

This suppression ultimately leads to a significant reduction in sex hormone levels, specifically testosterone in men and estrogen in women. This hormonal deprivation is therapeutically beneficial in conditions that are hormone-sensitive, such as prostate cancer, endometriosis, and uterine fibroids, by inhibiting the growth and activity of these tissues.

Uses

• Prostate cancer
• Endometriosis
• Uterine fibroids
• Precocious puberty

Directions For Use

Administer subcutaneously or intranasally as prescribed by a healthcare professional.

Benefits

• Suppresses sex hormone production
• Effective in hormone-sensitive cancers
• Reduces symptoms of endometriosis
• Shrinks uterine fibroids
• Manages precocious puberty effectively
• Available in various formulations for convenience

Side Effects

• Hot flashes
• Decreased libido
• Injection site reactions
• Headache
• Mood changes
• Bone density loss
• Vaginal dryness
• Breast tenderness
• Nausea
• Fatigue
• Weight changes
• Muscle pain

Safety Measures

• Alcohol - No specific contraindication, but excessive alcohol may exacerbate hot flashes or mood changes.
• Pregnancy - Contraindicated during pregnancy as it may cause fetal harm. Use effective contraception during treatment.
• Breastfeeding - Not recommended during breastfeeding due to the potential for hormonal effects on the infant.
• Liver - Use with caution in severe hepatic impairment; monitor liver function periodically.
• Kidney - Use with caution in severe renal impairment; monitor renal function periodically.
• Lung - No specific contraindications related to lung conditions.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.