Bdparp 100mg Tablet 28'S

About

Bdparp 100mg Tablet is a targeted antineoplastic agent, specifically a PARP (Poly ADP-ribose polymerase) inhibitor, used in the treatment of certain cancers. Its primary mechanism of action involves blocking the PARP enzymes, which are critical for the repair of single-strand DNA breaks in cells. In cancer cells, particularly those with homologous recombination deficiency (e.g., BRCA1/2 mutations), inhibiting PARP leads to an accumulation of DNA damage, ultimately resulting in cell death. This synthetic lethality approach makes Bdparp highly effective in treating specific types of ovarian, breast, prostate, and pancreatic cancers. It is typically administered orally, either as a monotherapy or in combination with other agents, often as maintenance therapy following initial chemotherapy. Patient selection often involves genetic testing to identify those most likely to benefit. Close monitoring for hematological toxicities, such as anemia and neutropenia, and other adverse effects is crucial throughout the treatment period to ensure patient safety and optimize therapeutic outcomes.

Uses

• Maintenance therapy for recurrent ovarian cancer.
• Treatment of BRCA-mutated metastatic breast cancer.
• Management of metastatic castration-resistant prostate cancer.
• Therapy for BRCA-mutated metastatic pancreatic cancer.

Directions For Use

Take Bdparp 100mg Tablet orally twice daily, with or without food, as prescribed by your doctor. Swallow the tablets whole; do not chew, crush, or break them.

Benefits

• Inhibits PARP enzymes for DNA repair.
• Highly effective in BRCA-mutated cancers.
• Extends progression-free survival.
• Reduces the risk of disease progression.
• Convenient oral dosing regimen.
• Improves patient outcomes in targeted populations.

Side Effects

• Nausea and vomiting
• Fatigue and asthenia
• Anemia (low red blood cells)
• Neutropenia (low white blood cells)
• Thrombocytopenia (low platelets)
• Abdominal pain
• Diarrhea or constipation
• Decreased appetite
• Headache
• Dyspepsia (indigestion)
• Myelosuppression
• Pneumonitis (rare)

Safety Measures

• Alcohol - Limit alcohol intake as it may exacerbate gastrointestinal side effects or contribute to fatigue.
• Pregnancy - Bdparp is contraindicated during pregnancy due to potential embryofetal toxicity. Women of childbearing potential must use highly effective contraception.
• Breastfeeding - Breastfeeding is not recommended during treatment with Bdparp and for at least one month after the last dose, as the drug may pass into breast milk.
• Liver - Use with caution in patients with moderate to severe hepatic impairment; dose adjustments may be necessary, and liver function should be monitored.
• Kidney - Caution is advised in patients with moderate to severe renal impairment; dose modifications may be required, and kidney function should be regularly assessed.
• Lung - Monitor for new or worsening respiratory symptoms, such as shortness of breath or cough, as pneumonitis is a rare but serious side effect.

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