Bdparp 150mg Tablet 56'S

About

Bdparp 150mg Tablet is an advanced antineoplastic agent belonging to the class of PARP (Poly ADP-ribose polymerase) inhibitors. This medication is specifically designed to target and inhibit PARP enzymes, which are crucial for DNA repair in cells. By blocking PARP, Bdparp prevents cancer cells, particularly those with existing DNA repair defects (like BRCA mutations), from effectively repairing their DNA damage, leading to their death. This targeted approach makes it highly effective in certain types of cancers, such as ovarian, breast, prostate, and pancreatic cancers, especially in patients with specific genetic mutations. It is typically administered orally as a maintenance therapy or for the treatment of advanced disease. The dosage and treatment duration are determined by the oncologist based on the patient's genetic profile, cancer type, and response to therapy. Close monitoring for hematological toxicities and other adverse effects is essential throughout the treatment course.

Uses

• Maintenance treatment of recurrent ovarian cancer.
• Treatment of BRCA-mutated metastatic breast cancer.
• Management of metastatic castration-resistant prostate cancer.
• Therapy for BRCA-mutated metastatic pancreatic cancer.

Directions For Use

Take Bdparp 150mg Tablet orally twice daily, with or without food, as prescribed by your doctor. Swallow the tablets whole; do not chew, crush, or break them.

Benefits

• Targets DNA repair pathways in cancer cells.
• Effective in BRCA-mutated cancers.
• Extends progression-free survival.
• Reduces risk of cancer recurrence.
• Oral administration for convenience.
• Improves overall survival in specific indications.

Side Effects

• Nausea and vomiting
• Fatigue and asthenia
• Anemia (low red blood cells)
• Neutropenia (low white blood cells)
• Thrombocytopenia (low platelets)
• Abdominal pain
• Diarrhea or constipation
• Decreased appetite
• Headache
• Dysgeusia (taste disturbance)
• Myelosuppression
• Pneumonitis (rare)

Safety Measures

• Alcohol - Limit alcohol intake as it may exacerbate gastrointestinal side effects or contribute to fatigue.
• Pregnancy - Bdparp is contraindicated during pregnancy due to potential embryofetal toxicity. Women of childbearing potential must use highly effective contraception.
• Breastfeeding - Breastfeeding is not recommended during treatment with Bdparp and for at least one month after the last dose, as the drug may pass into breast milk.
• Liver - Use with caution in patients with moderate to severe hepatic impairment; dose adjustments may be necessary, and liver function should be monitored.
• Kidney - Caution is advised in patients with moderate to severe renal impairment; dose modifications may be required, and kidney function should be regularly assessed.
• Lung - Monitor for new or worsening respiratory symptoms, such as shortness of breath or cough, as pneumonitis is a rare but serious side effect.

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