Imatirel 400mg Tablet 10's

About

Imatirel tablet contains imatinib, an antineoplastic agent classified as a tyrosine kinase inhibitor. It is prescribed for the treatment of both adults and children diagnosed with chronic myeloid leukaemia (CML), a type of cancer where abnormal white blood cells multiply uncontrollably. It is also used to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph-positive ALL).

Additionally, Imatirel is effective in managing gastrointestinal stromal tumours (GIST)—a type of tumour that develops in the walls of the digestive tract and may spread to other areas of the body. The medication is also used for treating myelodysplastic/myeloproliferative diseases (MDS/MPD), a group of blood disorders characterized by uncontrolled blood cell growth. It is indicated for hypereosinophilic syndrome (HES) and chronic eosinophilic leukaemia (CEL), conditions involving excessive growth of eosinophils (a type of white blood cell). Imatirel is also used in the treatment of dermatofibrosarcoma protuberans (DFSP), a rare cancer affecting the tissue beneath the skin.

Imatirel works by inhibiting the growth and spread of abnormal blood cells.

Do not take Imatirel if you are allergic to imatinib or any of the ingredients in the tablet. Before beginning treatment, inform your doctor if you have any liver, kidney, or heart conditions, thyroid disorders, or if you have had your thyroid gland removed. Also, let your doctor know if you currently have or previously had hepatitis B, as this medication can cause the virus to reactivate.

While on Imatirel, promptly report symptoms such as unexplained bruising or bleeding, fever, fatigue, or confusion. Be aware that this medicine may affect fertility.

• Chronic myeloid leukemia (CML)
• Philadelphia chromosome positive acute lymphoblastic leukemia (ph-positive ALL)
• Myelodysplastic/myeloproliferative diseases (MDS/MPD)
• Hypereosinophilic syndrome (HES)
• Chronic eosinophilic leukemia (CEL)
• Dermatofibrosarcoma protuberans (DFSP)
• Gastrointestinal stromal tumors (GIST)

Directions for use

This medicine should be administered by a doctor or nurse. Please do not attempt to self-administer it.

Common:

• Swelling in the face, legs, ankle and feet
• Nausea, vomiting
• Muscle cramps and pain
• Diarrhea
• Skin rash, night sweats
• Tiredness, dizziness
• Abdominal pain
• Increased weight
• Decreased RBC and WBC cells
• Headache
• Cough, Inflammation in the nose
• Fever, lack of sleep

Serious:

• Heart failure
• GI disorders
• Hypothyroidism
• Liver failure
• Swelling in the body

Safety Measures

Alcohol - It is not known whether consuming alcohol while taking Imatirel tablets is safe. It is advisable to consult your doctor for personalized guidance based on your condition and overall health.
Pregnancy - Imatirel tablets are not safe for use during pregnancy, as they may harm the developing fetus. Inform your doctor if you are pregnant, think you might be pregnant, or are planning to conceive. It is essential to use effective contraception during treatment and for at least 15 days after the final dose.
Breastfeeding - Breastfeeding is not advised while taking Imatirel tablets, as the medication can pass into breast milk in small amounts and may pose a risk to your baby.
Liver - Imatirel tablets are unsafe for use in patients with severe liver disease. Dose adjustments may be required in cases of severe liver impairment. Inform your doctor about any existing liver conditions before starting the treatment.
Kidney - It is not known whether Imatirel tablets are safe for patients with kidney disorders. Consult your doctor if you have any lung conditions before beginning the treatment.


Disclaimer

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