Parbraze 100mg Tablet

About

This medication belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs), primarily functioning by inhibiting cyclooxygenase (COX) enzymes, particularly COX-2, which are responsible for the synthesis of prostaglandins. Prostaglandins are key mediators of inflammation, pain, and fever in the body. By reducing prostaglandin production, the drug effectively alleviates pain, reduces inflammation, and lowers fever, offering symptomatic relief. It is commonly used for the management of various musculoskeletal and inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Its analgesic and anti-inflammatory properties work to improve patient comfort, enhance mobility, and reduce swelling, thereby improving quality of life for individuals suffering from chronic inflammatory pain.

Uses

• Relief of pain and inflammation in osteoarthritis.
• Management of rheumatoid arthritis symptoms.
• Treatment of ankylosing spondylitis.
• Alleviation of acute musculoskeletal pain.

Directions For Use

Take one tablet orally, usually once or twice daily, with food or after meals to minimize gastrointestinal upset.

Benefits

• Effective pain relief.
• Reduces inflammation and swelling.
• Improves joint mobility.
• Provides symptomatic relief for chronic conditions.
• Helps manage fever.
• Generally well-tolerated with food.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Dyspepsia
• Heartburn
• Dizziness
• Headache
• Rash
• Fluid retention
• Increased blood pressure
• Gastric ulcers (with prolonged use)

Safety Measures

• Alcohol - Concurrent use of alcohol with NSAIDs can increase the risk of gastrointestinal bleeding and irritation. It is advisable to avoid or limit alcohol.
• Pregnancy - Generally not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus and complications during delivery.
• Breastfeeding - Small amounts may pass into breast milk. Use with caution and only if clearly necessary, under medical advice.
• Liver - Use with caution in patients with liver impairment. Dose adjustment may be necessary, and liver function should be monitored.
• Kidney - Use with caution in patients with kidney impairment as NSAIDs can affect renal function. Regular monitoring of kidney function is recommended.
• Lung - Use with caution in patients with asthma, as NSAIDs can sometimes trigger bronchospasm in susceptible individuals.

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